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Medical scientist Kris spends over 22 hours a week keeping his three bedroom home in Wakefield germ free and he attempts to help single mum Edwina and her teenage daughter Natalie in Derby who haven't deep cleaned their house since they moved in nearly a ten years ago. TOCD diagnosed 41-year-old beauty therapist Fiona from Bedford attempts to help married couple Jenny and Paul in Surrey, whose three bedroom house has become overwhelmed with clothes, toys and games.