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Professor Robert Winston presents his top ten scientific breakthroughs of the past 50 years. Tracing these momentous and wide-ranging discoveries, he meets a real-life bionic woman, one of the first couples to test the male contraceptive pill, and even some of his early IVF patients. He explores the origins of the universe, probes the inner workings of the human mind and sees the most powerful laser in the world. To finish, Professor Winston reveals the breakthrough he thinks is most significant.